Research Trials

Check out the list below of some investigator-led clinical trials currently recruiting across Canada. If you click on “Learn More”, you will be taken to the clinicaltrials.gov listing for more information about the principal investigator and trial site locations.

If you are an investigator and would like your trial listed, please contact Alicia at amurdoch@cansolveckd.ca.

TitleStatusCondition(s)Link
AFTER AKI: Improving Post Discharge Care After Acute Kidney InjuryRecruitingAcute Kidney Injury (AKI)Learn more
SUPPORT AKI: Strategy for Uptake of Processes for Recognizing and Responding to Acute Kidney InjuryActive, not recruitingAcute Kidney Injury (AKI)Learn more
Contrast RISK: Reducing Injury Sustained by KidneysActive, not recruitingAcute Kidney Injury (AKI)Learn more
FUSION: Nephrologist Follow-up Versus Usual Care After an Acute Kidney Injury HospitalizationActive, not recruitingAcute Kidney Injury (AKI)
Chronic Kidney Disease (CKD)
Learn more
ECHO-AKI: Ultrasound Markers of Organ Congestion in Severe Acute Kidney InjuryRecruitingAcute Kidney Injury (AKI)Learn more
Integrating Risk-based Care for Patients With CKDRecruitingChronic Kidney Disease (CKD)Learn more
Evaluation of Fructose Ingestion and the Renin Angiotensin System in HumansRecruitingChronic Kidney Disease (CKD)Learn more
Reducing Hemodialysis Induced Recurrent Brain Injury to Improve Patients' LivesRecruitingChronic Kidney Disease (CKD)Learn more
MPAC-CKD: Micro-Particle Curcumin for the Treatment of Chronic Kidney DiseaseActive, not recruitingChronic Kidney Disease (CKD)Learn more
EMPATHY: Evaluation of Routinely Measured Patient-reported Outcomes in Hemodialysis CareRecruitingChronic Kidney Disease (CKD)
Hemodialysis
Learn more
Kidney Check: Diabetes, Blood Pressure & Kidney Health Checks & Care in Indigenous Communities.RecruitingChronic Kidney Disease (CKD)
Diabetes
Hypertension
Learn more
The Effect of Previous Pneumococcal Immunization on the Immune Response of Patients With Severe CKD to Prevnar 13Active, not recruitingChronic Kidney Disease (CKD)Learn more
Clinical Evaluation of PROMIS in CKDActive, not recruitingChronic Kidney Disease (CKD)Learn more
PHARMACO-$: Comparing the Hemodiafiltration On-line and Conventional Hemodialysis in Terms of Cost-benefitActive, not recruitingChronic Renal Failure
Hemodialysis
Learn more
Transition Navigator Trial (TNT): Evaluating Innovations in Transition From Pediatric to Adult CareRecruitingDiabetes
Renal
Learn more
D-LITE: Dialysis-Less Frequently In The ElderlyRecruitingEnd Stage Renal Disease (ESRD)
Hemodialysis
Learn more
Dyspnea Assessment in Hemodialysis PatientsRecruitingEnd Stage Renal Disease (ESRD)
Hemodialysis
Learn more
Development of a 'Phosphate Counting Program'Active, not recruitingEnd Stage Renal Disease (ESRD)Learn more
Effect of Extended Dialysis on Patient Reported Symptoms Using LEVILRecruitingEnd Stage Renal Disease (ESRD)Learn more
Second Clinical Evaluation of THERANOVA-500 Dialyzer in Chronic Hemodialysis (HD)RecruitingEnd Stage Renal Disease (ESRD)
Hemodialysis
Learn more
Targeted Deprescribing in Patients on HemodialysisNot yet recruitingEnd Stage Renal Disease (ESRD)
Hemodialysis
Learn more
DISCO-RLS: DIalysis Symptom COntrol-Restless Legs Syndrome TrialRecruitingEnd Stage Renal Disease (ESRD)
Restless Legs Syndrome
Learn more
SAVE: Sirolimus Use in Angioplasty for Vascular Access ExtensionRecruitingEnd Stage Renal Disease (ESRD)
Venous Stenosis
Learn more
iPACK-HD: Vitamin K to Attenuate Coronary Artery Calcification in Hemodialysis PatientsActive, not recruitingEnd Stage Renal Disease (ESRD)Learn more
RESOLVE: Randomised Evaluation of Sodium Dialysate Levels on Vascular EventsRecruitingEnd Stage Renal Disease (ESRD)Learn more
ACCESS HD: Comparing Catheters to Fistulas in Elderly Patients Starting HemodialysisRecruitingEnd stage Kidney FailureLearn more
ACHIEVE: Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal DiseaseRecruitingEnd Stage Renal Disease (ESRD)Learn more
Cardiovascular and Respiratory Assessment Using Biometric Signals in a Non-contact Monitoring DeviceRecruitingEnd Stage Renal Disease (ESRD)Learn more
CONNECT: Assessment of Telehome Monitoring in Patients on Peritoneal DialysisRecruitingEnd Stage Renal Disease (ESRD)Learn more
Effect of an Exercise Rehabilitation Program on Symptoms in HemodialysisRecruitingEnd Stage Renal Disease (ESRD)
Hemodialysis
Learn more
CGNR:The Canadian Glomerulonephritis Registry and Translational Research InitiativeRecruitingGlomerular NephritisLearn more
Sodium Deposition in Soft Tissues of Patients With Kidney DiseaseRecruitingHemodialysisLearn more
ENCOMPASS: Enhancing Community Health Through Patient Navigation, Advocacy and Social SupportRecruitingDiabetes
Chronic Kidney Disease (CKD)
Learn more
TESTING: Therapeutic Evaluation of Steroids in IgA Nephropathy Global Study (TESTING Low Dose Study)Active, not recruitingIgA GlomerulonephritisLearn more
PLATO: Medication Adherence in Transplant RecipientsRecruitingChronic Kidney Disease (CKD)
Transplant
Learn more
DIAL-Mag: Outcomes of a Higher vs. Lower Hemodialysate Magnesium ConcentrationNot yet recruitingEnd Stage Renal Disease (ESRD)
Hemodialysis
Learn more
MyTEMP: Major Outcomes With Personalized Dialysate TEMPeratureActive, not recruitingEnd Stage Renal Disease (ESRD)
Hemodialysis
Learn more
EnAKT LKD: Enhance Access to Kidney Transplantation and Living Kidney DonationActive, not recruitingKidney Failure
End Stage Renal Disease (ESRD)
Learn more
EPURE: Modalities of Renal Replacement Therapy in Pediatric Acute Kidney InjuryActive, not recruitingAcute Kidney FailureLearn more
NEPTUNE: Nephrotic Syndrome Study NetworkRecruitingMinimal Change Disease (MCD)
Membranous Nephropathy
Glomerulosclerosis, Focal Segmental
Learn more
INSIGHT: Insight Into Nephrotic SyndromeRecruitingNephrotic SyndromeLearn more
CHILDNEPH: The Canadian Childhood Nephrotic Syndrome StudyRecruitingNephrotic SyndromeLearn more
DIAT: Dietary Intervention in ADPKD on TolvaptanRecruitingAutosomal Dominant Polycystic Kidney Disease (ADPKD)Learn more
Fatigue-HD: Pilot Study of an Educational Program for Adults on Hemodialysis With FatigueRecruitingHemodialysisLearn more
End Stage Renal Disease Tobramycin Administered at the Beginning of DialysisRecruitingRenal Dialysis
Chronic Renal Failure
Learn more
Exercise in Patients With End Stage Kidney DiseaseRecruitingRenal FailureLearn more
Effect of Vitamin D3 Supplementation on Arterial and Bone Remodeling in Chronic Kidney Disease PatientsActive, not recruitingChronic Kidney Disease (CKD)Learn more
iCARE: Improving Renal Complications in Adolescents With Type 2 Diabetes Through REsearch Cohort StudyRecruitingType 2 Diabetes
Nephropathy
Learn more
PDE5i Use in Renal Transplant RecipientsNot yet recruitingTransplantLearn more
Oxygenated Machine Preservation in Kidney TransplantationNot yet recruitingTransplantLearn more
The Effect of a Prehabilitation Exercise Program on Physical Functioning for Patients Undergoing Kidney TransplantationRecruitingEnd Stage Renal Disease (ESRD)
Transplant
Learn more
Enhance Access to Kidney Transplantation and Living Kidney DonationActive, not recruitingEnd Stage Renal Disease (ESRD)
Transplant
Learn more
Evaluation of Thiosulfate in End Stage Renal Disease and Kidney TransplantationNot yet recruitingTransplantLearn more
Once Daily Dosing to Improve Medication Adherence and Patient Satisfaction in Kidney Transplant RecipientsActive, not recruitingTransplantLearn more
Video Education and Behaviour Contract to Optimize Adherence in Renal TransplantsRecruitingTransplantLearn more
Drug Interaction Study of Apixaban With Cyclosporine or Tacrolimus in Transplant RecipientsRecruitingTransplantLearn more
Urine CXCL10 Monitoring Trial in Kidney TransplantRecruitingTransplantLearn more